Retinal Vascular Disease Overview

Retinal Vascular Diseases

Introduction ¹

The retina consists of 10 layers including inner and outer limiting membranes, neuronal layer, rods and cones; these layers require a continuous blood supply and nutrients in order to function optimally. The vascular system of the retina consists of arteries, capillaries and veins. Blockage of any of these blood vessels results in retinal vascular disease or retinal vascular occlusion.

A growth factor named vascular endothelial growth factor A (VEGF-A) controls angiogenesis – the growth of new blood vessels; that is thought to be implicated in retinal vascular disease. In the presence of systemic diseases such as diabetes and atherosclerosis, the retinal blood vessels can undergo a variety of changes.


Types ²




Causes of Retinal Vascular Disease ¹


Diagnosis ²

Early diagnosis and management are critcal to prevent permanent damage to vision due to the potentially rapidly progressive nature of retinal vascular disease.  Depending on the presentation there are multiple tests that may be performed:

Treatment ³

Treatment of retinal vascular disease has improved in recent times due to the development and use of anti-VEGF medications. The reversibility of vision depends upon the stage and time of presentation. A patient-centered approach is critical.


Uncontrolled systemic disease and late presentation can result in severe or permanent loss of vision. The following complications may occur in retinal vascular disease:



If you have not already, make sure to contact your eye care specialists at Eye Surgeons Associates for a complete dilated exam soon!


1- Retinal Vascular Disorder - an overview | ScienceDirect Topics. (n.d.). Sciencedirect.Com. Retrieved October 10, 2021, from

2- Gabbey, A. E. (2017, April 11). Retinal Vascular Occlusion. Healthline.

3- Management of retinal vascular diseases: a patient-centric approach. (2012, April 1). PubMed Central (PMC).

Eye Surgeons Associates Drs. Meiraj A. Siddiqui, Zuhair H. Peracha, Manal H. Peracha-Riyaz, Eric Zuckerman and Leila Siblani are dedicated to excellence in eye care and service. We utilize the latest treatment methods and procedures, including routine eye care, cataract surgery, glaucoma treatment, retinal disease management, diabetic eye treatment, and eyelid surgery.

You Might Also Enjoy...

What is Ectropion?

Ectropion is a condition in which your eyelid turns outward. This months blog details what the signs and symptoms of ectropion are and how you or your loved one can best treat it.

Treatment of Conjunctivitis

Conjunctivitis can be either bacterial or viral. Treatment varies, so be sure to see a professional for a proper diagnosis. Details are provided for you in this month's blog post.

Ocular Pruritus Explained

Itchy eyes is normal to experience at one time or another. If it continues to be bothersome, contact us. Your eye health is of upmost importance!

What is a Chalazion?

A chalazion is normally painless, however symptoms should not be ignored. Find out more in this months blog.

Eyelashes Gone Awry

Where your eyes are concerned, small things matter. This month we cover all you need to know about a condition called trichiasis. When something as simple as your eyelashes is a concern that needs to be addressed.

What is Entropion?

Below we will cover the signs, symptoms, and causes of the condition entropion. Are you at risk of developing it? Take the time to read this months featured discussion and find out.